Genetic Resources

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Statement of Purpose

Researchers associated with natural history museums have made the collection of genetic resources a priority due to their importance in molecular studies, but often the long-term curation of these collections is difficult due to decentralized curation over multiple storage locations and lack of community best practice guidelines for their stewardship. Unlike traditional natural history specimens, the research utility of genetic samples increases with lower storage temperatures and fewer freeze–thaw events and, in addition, their use is consumptive. Collection managers must, therefore, maximize the research potential of each sample by carefully considering use on a case-by-case basis. This page presents standardized guidelines for the management of genetic collections associated with natural history collections. These recommended practices are informed by general standards for biorepositories and augmented by information unique to natural history collections with the goal of providing a foundation for those curating genetic samples. Information pertains to all aspects of genetic sample curation and will assist those in making decisions regarding how to collect, store, track, process, and distribute genetic specimen samples. These guidelines also will allow users to make informed decisions regarding how to apply and improve the curation of their collection given their institution’s goals and available resources.

Introduction

Developing Policies

Funding and Budgets

Facility Management

Access and security

Space planning

Lighting

Flooring

Ventilation

Oxygen monitors

Backup precautions

Genetic and Genomic Collections Storage

Temperature considerations

Liquid nitrogen cryovats

Liquid nitrogen supply

Mechanical freezers and refrigerators

Operational Best Practices

Facility functions and services provided

Personnel

Training

Manual monitoring

Equipment preventative maintenance, repair, and replacement

Records management

Emergency procedures

Genetic Sampling Processing

Storage containers

Sample Transfer

Inventory Control and Data Management

Sample labeling and tracking

Databasing for genetic samples

Use of Collections

Loan policies

Aliquoting samples

Packaging and shipping loans/gifts

Health & Safety

General laboratory practices

Personal protective equipment

Liquid nitrogen safety

Dry ice safety

Biosafety

Chemical safety

Fire safety

Ethical and Legal Best Practice

Contributors

Breda Zimkus, Linda Ford

Source Material

Zimkus, Breda M. and Linda Ford Media:Zimkus Ford 2014 Best Practices.pdf Best Practices for Genetic Resources Associated with Natural History Collections Recommendations for Practical ImplementationPdf logo - small.gif, 2014. Collection Forum 28(1-2), pp. 77-112. Society for the Preservation of Natural History Collections.

Links

Consensus Documents

Community Standards

Review Documents

References


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